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Some enzymes, including blue copper proteins, overcome this problem by utilizing hybrid active sites, which stabilize both redox states, in a single pocket, but each with different geometries 10

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[37] More than a dozen peptides and other substances have been isolated from the Gila monster's venom, including hyaluronidase, serotonin, phospholipase A 2 , and several kallikrein-like glycoproteins responsible for the pain and edema caused by a bite, without producing a compartment syndrome

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