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We report that dual blockade with our fully human GDF8 and ActA blocking antibodies during GLP-1 RA-treatment of obese mice and NHPs preserves lean mass, while also increasing fat loss and improving metabolic measures

In early studies, people on higher doses of retatrutide lost more than 20 percent of their body weight on average, which is higher than the results seen with many current drugs

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If the vial had previous room temperature exposures before this week, add them together

Your doctor will determine your best maintenance dose based on several factors: how much weight youve lost, how you handle side effects, and how your body responds to treatment