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Recently we have shown that GLP-1 activates afferent renal nerves to increase efferent renal sympathetic nerve activity that negates the diuresis and natriuresis produced by GLP-1 in normal rats [24]

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Zalewski A, Krajewski PK, Szepietowski JC

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The article says the switch requires medical oversight because bioavailability, injection technique and storage protocols may differ slightly between formulations