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Some experts worry that broader availability to certain peptides through compounding pharmacies could expose larger numbers of patients to therapies whose long-term safety profiles remain unclear

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Although it is likely that abnormalities in brain structure and activation exist outside this canonical circuit (see for example Menzies et al., 2008), these functional and morphological data have focused attention on the CSTC circuitry as we strive to understand the neuropathophysiology of OCD and to develop novel treatment strategies