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Dosing protocols

The cost of drugs constitutes a large percentage of overall reimbursement of infusion therapy

45,46 While additional trials in patients with HFpEF are warranted before definitive statements can be made regarding the benefits of various incretin therapies in HFpEF, providers may wish to consider the positive results for semaglutide and tirzepatide when choosing among incretin therapies

Acknowledgments We thank the Laboratrio de Biomedicina Mitocondrial e Teranstica, Centro de Neurocincias e Biologia Celular for the assistance with RNA integrity analysis