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What was the dose

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Notably, like other cholesterol biosynthesis inhibitors, triparanol activated transcription of cholesterol biosynthetic genes SQLE and FDFT1 , indicating a functional consequence of DHCR24 inhibition (Supplementary Fig

In contrast, COX-1 is normally active in many tissues, where it has roles unrelated to inflammation (e.g., clotting function in blood platelets, mucus production from cells lining the GI tract) (Toussaint 2010