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Description

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HFD and Met and choline-deficient diet (MCD) can mimic human diseases histological and metabolic abnormalities and are commonly used to establish NAFLD mouse models

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Recent data also suggest that hydroxyurea may upregulate GPx-1 expression in several cell lines and in circulating erythrocytes, in part, by a p53-dependent pathway, providing evidence that p53-mechanisms modulate GPx-1 expression in vivo (68)

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