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By altering hunger signals in the brain, GLP-1 promotes a feeling of fullness, reduces cravings, and supports sustainable weight loss

Timing Recommendations: Pre-Workout: Enhances fat burning during exercise

[19] A 2011 Cochrane review showed a HbA1c reduction of 0.24% more with liraglutide 1.8 mg compared to insulin glargine, 0.33% more than exenatide 10 g twice daily, sitagliptin and rosiglitazone

Common observations during this period include skin texture feeling slightly less plump or firm, fine lines that had completely disappeared beginning to reappear subtly, and overall skin quality remaining better than pre-treatment but noticeably less optimal than peak treatment results

The trade-off is that it requires the skin to go through a disruption phase, and many people find it hard to use consistently enough to get the full benefit