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Individuals with Fitzpatrick skin types I or II (very fair, minimal natural melanin) often require higher initial doses (0.50.75mg) to overcome the naturally low baseline tyrosinase activity in their melanocytes

This recycling process is vital for maintaining cellular health

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In initial testing, Melanotan II did induce tanning but additionally caused sexual arousal and spontaneous erections as unexpected side effects in nine out 10 original volunteer test subjects

Digestive issues, dietary choices or increased nutrient needs can make it harder for the body to absorb and use vitamin C effectively