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To support their rapid proliferation and invasive metastasis, cancer cells exhibit abnormally high metabolic activity, leading to excessive activation of ROS-producing enzymatic systems, thus generating higher levels of H 2 O 2 than normal cells (203206)

Annu Rev Plant Biol 58:347375 Rossini L, Jepson I, Greenland AJ, Gorla MS (1996) Characterization of glutathione S-transferase isoforms in three maize inbred lines exhibiting differential sensitivity to alachlor

363,364 This inhibition is believed to occur through the suppression of LPS-induced TNF- production in macrophages