The drug also reduced pain scores by an average of 4.5 points, representing a 75.8% improvement, while more than 1 out of 8 patients became completely free from knee pain by the end of the trial
Pancreatitis (rare): GLP-1 medications have a very small risk of pancreatitis (inflammation of the pancreas)
The optimization process achieved a cumulative fitness improvement of 2.351 units, with the best-performing sequence reaching a final fitness score of 60.743, representing a 4.0% enhancement from the initial population (Figure 7)
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[5] Unlicensed medicines can, in limited circumstances, be supplied on a named-patient 'specials' basis under MHRA and GMC guidance but this applies only where there is a documented clinical need that cannot be met by a licensed product, and it does not extend to cosmetic, body composition, or weight-loss indications
