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Carcinogenesis 29:102232 Natarajan VT, Singh A, Kumar AA (2010) Transcriptional upregulation of Nrf2-dependent phase II detoxification genes in the involved epidermis of vitiligo vulgaris

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Discussion The mechanism of pancreatic fibrosis in PSCs in chronic inflammation or pancreatic cancer is well known, but studies focusing on the potential role in islet fibrosis and -cell failure are limited [10, 11]

The peptide backbone provides three coordination sites for copper: the free alpha-amino group of glycine, the deprotonated amide nitrogen of the glycyl-histidyl bond, and the imidazole nitrogen of the histidine side chain, with the lysine epsilon-amine remaining available for further interactions