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While no evidence confirms harm, absence of evidence does not confirm safety

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In tendon repair models where avascular healing is a well-recognized limitation BPC-157 administration in Wistar rat Achilles tendon transection experiments produced statistically significant increases in vessel density within the repair zone at 14 days post-transection compared to saline controls, accompanied by increased tensile strength measurements consistent with more mature, vascularized repair tissue

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Systemic effects including cognitive benefits, mood regulation, and general tissue maintenance could work with either route, though injection delivers more predictable exposure levels