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Patients with diabetes are at an increased risk for periodontal disease

"Constipation from GLP-1s can be compounded by the fact that people are eating less," says Hamilton, "resulting often in less fiber consumption and less stool bulk overall." Many people also drink less fluid to avoid feeling overly full on GLP-1 medications, which can also lead to constipation

In chronic pain and depression, morphological and functional neuroplastic changes were found most pronounced in fronto-limbic regions (Mutso et al., 2012

This translates to people on Zepbound losing roughly 50 pounds compared to 33 pounds on Wegovy during the 72-week trial

Glycine is the simplest amino acid, and adding it to GLP-1 formulations is thought to improve stability and reduce injection site reactions