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This release of histamine is what typically triggers allergy symptoms such as sneezing, itching, and inflammation

Effective half-life in clinical pharmacology

Moreover, Lf can interact through the C-lobe with the HA2 fragment of hemagglutinin, a glycoprotein present on the envelope of the virus that has a fundamental role in allowing binding to cells and penetration of the virus (Gruden and Poklar Ulrih 2021)

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The BBB is the critical boundary of the central nervous system (CNS) where it maintains intracellular homeostasis and facilitates communication with the peripheral circulation