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It also improves sleep quality and circadian rhythm regulation and enhances mitochondrial function, meaning your cells literally produce energy more efficiently. 4

The results showed a consistent advantage for the combination, and that advantage became more pronounced at higher weight loss thresholds, precisely where GLP-1 therapy tends to be most clinically meaningful: At a 20% weight loss threshold, 45% of women in the combination group achieved this level of loss, compared to 24% in the GLP-1 alone group

IC 95% 0,693,59) n nei trial randomizzati (Liu et al., 2025)

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However, this process begins to shift when a person is around their 30s or 40s