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doi: 10.1016/S0021-9258(19)81312-1

For example, ER stress activates DNA damage inducible transcript 3 (DDIT3, also known as CHOP)- and mitogen-activated protein kinase 8 (MAPK8, also known as JNK)-dependent apoptosis pathways, whereas heat shock protein family A member 5 (HSPA5, also known as BIP) SSG at Cys420/441 modulates ATPase activity and protein folding, paradoxically suppressing apoptosis 49

This includes optimising control of type 2 diabetes, hypertension, and dyslipidaemia, all of which commonly coexist with fatty liver disease

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