This aligns with the research, as GLP-1-stimulating effects may be most pronounced before meals
[DOI] [Google Scholar] 83.Wang Z., Wang C., Qiu J., Ni Y., Chai S., Zhou L., Li J., Yan B., Yang J., Liu Q
How Long Does Retatrutide Remain Active in the Body
This may be because elevated interleukin-6 (IL-6) concentrations in response to exercise stimulate PYY and GLP-1 levels [16] and suppress ghrelin expression [17], along with a redistribution of blood flow from gut hormone release sites to active muscles that may decrease acylated ghrelin due to decreased activity of the ghrelin O-acyl transferase (GOAT) enzyme, which is required to acylate ghrelin into its active form [18]
doi: 10.3390/antiox8070229 114