Acknowledgements This insight article was supported by the National Natural Science Foundation of China (81901107) and the China Postdoctoral Science Foundation (2018M632872)
doi:10.1016/j.mce.2013.06.014 Watanabe I, Tomita A, Shimizu M, Sugawara M, Yasumo H, Koishi R, Takahashi T, Miyoshi K, Nakamura K, Izumi T, Matsushita Y, Furukawa H, Haruyama H, Koga T (2003) A study to survey susceptible genetic factors responsible for troglitazone-associated hepatotoxicity in Japanese patients with type 2 diabetes mellitus
doi: 10.1073/pnas.261469998
Zh 55 (3), 2636
In isolated human islets, somatostatin is released in response to increasing glucose concentrations ( Endogenous somatostatin is regulated by intra-islet paracrine influences ( The emerging picture of healthy glucose-insulin secretion coupling is less an isolated -cell driven action, but more a finely tuned paracrine counterbalance between all islet cell components