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Rather than preserving existing hormones, Ozempic directly activates GLP 1 receptors throughout the body, approximately 50 times more potently than natural GLP 1

However, these side effects usually go away after a few weeks of treatment

GLP-1/GIP Agonists: Mechanism and Clinical Outcomes GLP-1 receptor agonists (semaglutide) activate the GLP-1 receptor, which regulates appetite, glucose control, and gastric emptying

Additionally, Wegovy slows gastric emptying, which prolongs the sensation of fullness after meals and contributes to reduced caloric intake

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