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Dysregulation of Immune Response in Patients With Coronavirus 2019 (COVID-19) in Wuhan, China

A synthetic analogue of alpha-melanocyte-stimulating hormone is called melanotan 2 (MT-2)

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In conclusion, our study revealed a previously unidentified function of the ER stress sensor protein IRE1 in determining cellular sensitivity to ferroptosis through regulating GSH availability, a finding that may lead to the development of treatment strategies for ferroptosis-associated normal tissue damage and improvement in the efficacy of existing cancer therapies