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Hum Genet 131 (1): 77-85, 2012

The mechanism mediating the ability of PYY to regulate food intake is contentious but likely involves alterations in gastric emptying, vagal neuronal signaling to the hypothalamus 200,203,204 , and direct endocrine activation of the ARC 200

Changes in appetite and body weight in response to long-term oral administration of the ghrelin agonist GHRP-2 in growth hormone deficient children