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CRISPR-Cas antimicrobials: challenges and future prospects

These novel findings are complemented by the demonstration of reduced GPx1 in the colon of mice with DSS-induced colitis [41, 42], murine colitis induced by knockout of GPx1 and GPx2 [43], and genome-wide association studies that note polymorphisms in antioxidant genes, including GPxs in IBD [44, 45]

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