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Limit carbonated beverages, sugar-free sweeteners (especially sorbitol and xylitol), and high-fat foods

GLP-1 agonists enhance insulin secretion from pancreatic beta cells only when blood glucose levels are elevated, a mechanism termed "glucose-dependent insulinotropic action." This physiological approach reduces the risk of hypoglycemia compared with sulfonylureas or exogenous insulin, though the risk increases when GLP-1 agents are combined with insulin or sulfonylureas, potentially requiring dose adjustments of these medications

Digestive side effects mainly occurred during the dose escalation phase and were mostly mild to moderate in severitylower starting doses seemed to lessen this severity

While often temporary, it can take months to fade and may require additional treatment