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GLP-1 acts through a specific G protein-coupled receptor, which is expressed in pancreatic islets, the central nervous system, lungs, kidneys, heart, intestine, and immune cells, explaining the numerous roles for GLP-1 signaling beyond blood glucose control (Zietek and Rath 2016)

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Open field test Rats were examined for behavior, location, and autonomic nervous system (ANS) to assess the cognitive functions