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Description

Clinical trials have demonstrated that GLP-1 RAs, such as liraglutide and semaglutide, reduce blood pressure across diverse populations with T2DM and obesity

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1c, 3c, d and Supplementary Figs

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The gliptins do not significantly modify the pharmacokinetic profile and exposure of other medicines, and vice versa

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Key points Obesity is a risk factor for developing osteoarthritis (OA), gout, rheumatoid arthritis (RA), psoriatic arthritis (PsA) and axial spondyloarthritis (axSpA), and is associated with higher disease activity and/or severity, and worse response to common treatments

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doi: 10.1016/j.redox.2017.11.002

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