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Description

Ten human TLRs that signal via 4 adaptor proteins and 2 initial kinases activate distal kinases that subsequently regulate transcription factors such as NFB and activator protein 1 (AP-1), that control gene expression

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Treatment-related adverse events included nausea, vomiting, and diarrhea, all of which were mild, transient, and consistent with the established safety profile of GLP-1/GLP-2 dual agonists

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