Michael Buontempo, a resident physician at Dartmouth-Hitchcock Medical Center, explains: Most hair shedding on GLP-1s looks like androgenetic alopecia unmasked by an episode of telogen effluvium driven by the magnitude of weight loss, rather than a direct drug toxicity. This means some people discover they have genetic hair loss when the telogen effluvium pulls away enough hair to reveal the underlying pattern
Recently, a seventh trial, PIONEER 6 showed noninferiority of oral semaglutide compared with placebo for 3P-MACE among 3,183 T2DM patients, 85% of whom had established CVD, followed for a median of approximately 1.3 years (59)
Early in treatment, temporary shifts in lens focus can blur vision and make a new prescription inaccurate
Tirzepatide starts to lower blood sugar levels shortly after starting treatment, with maximum effects typically seen after several weeks of consistent use
In practical terms: Tirzepatide offers well-documented, steady metabolic support and weight-loss results