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Utilizing the concept of elevating GLP-1 concentrations, DPP-4 inhibitors as oral agents and synthetic injectable, DPP-4 resistant GLP-1 receptor agonists (GLP-1RA) were introduced as treatment options for T2D therapy (3136)

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Spinocerebellar ataxia type 2 Spinocerebellar ataxia type 2a genetic neurodegenerative disorder due to a CAG repeat expansion mutation in the ATXN2 gene coding for the protein ataxin-2 63 has been associated to oxidative stress, in particular due to alterations in the enzymatic activity of antioxidant enzymes including GSTs 64

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