GI dysfunction, a common comorbidity in PD, further contributes to fluctuations in levodopa absorption and plasma concentrations, thereby triggering or exacerbating the on-off phenomenon [86, 87]
doi: 10.3389/falgy.2023.1199355 Received 03 April 2023 Accepted 18 May 2023 Published 06 June 2023 Volume 4 - 2023 Edited by Isaac Kirubakaran Sundar, University of Kansas Medical Center, United States Reviewed by Jess Miguel Garca-Menaya, University Hospital of Badajoz, Spain Hong Yong Peh, Brigham and Women's Hospital and Harvard Medical School, United States Updates Copyright 2023 Klein, Dijoux, Cheminant, Intes and Bouchaud
Phentermine is an appetite suppressant that affects the central nervous system and helps to reduce food cravings
Based on this evidence, the principle of senolytic approaches is to target Senecent Cell Anti-Apoptotic Pathways (SCAPs) by inhibiting or activating proteins which regulate this apoptosis resistance 8,9
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