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The most widely used plant segment, due to the concentration of secondary metabolites and their bioavailability, are the leaves [2,22,23], which are traditionally marketed in packages tied with string in the form of a necklace, after having been dried at ambient temperaturesFigure 1

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10.1016/j.jacc.2020.11.010 125 SamulakJ

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After verifying the results of the previous, highly controlled studies, the researchers expanded their study population to make it more reflective of HFpEF cases in clinical practice, finding that overall, the drugs were associated with a greater than 40% reduction in heart failure hospitalization or all-cause mortality as compared with sitagliptin