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Over-the-counter stool softeners (docusate) or gentle stimulant laxatives (senna, bisacodyl) may be necessary during the first 2 to 3 weeks, but most patients normalize bowel function as their body adapts to the medication

It is worth noting that clinical studies and post-marketing surveillance have identified an increased risk of gallbladder-related events with GLP-1 receptor agonists, including semaglutide, though the mechanism for this association is not fully understood

May 1 2021;doi:10.1007/s10815-021-02217-x Ramezani Tehrani F, Rahmati M, Mahboobifard F, Firouzi F, Hashemi N, Azizi F

Similarly, formulations that combine glutathione with Alpha Lipoic Acid (ALA) such as Glutone A can offer added benefits by targeting pigmentation while enhancing overall skin clarity and glow