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Hypoglycemia risk is low with semaglutide monotherapy because its glucose-lowering effect is glucose-dependent

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Because semaglutide causes delayed gastric emptying, patients undergoing sedation during surgery are at an increased risk for pulmonary aspiration

MACE= major adverse cardiovascular event, such as a heart attack or stroke

What We Know So Far Same indication: Oral Wegovy has the same FDA approval as injectable chronic weight management in adults with obesity or overweight plus a related health condition (comorbidity) Same PA criteria likely: Insurers who cover injectable Wegovy will likely apply the same BMI (body mass index), lifestyle documentation, and step therapy requirements (trying other medications first) Formulary delays expected: New drugs typically take 1-3 months to be added to formularies after launch Tier placement varies: Some insurers may place oral Wegovy on a non-preferred tier initially, with higher copays or additional PA hurdles Already denied