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3.3 Accelerating the recovery of exercise-induced fatigue 3.3.1 Role of UA in alleviating inflammatory responses The overtraining-cytokine hypothesis proposes that prolonged stress, insufficient recovery periods, and disrupted sleep patterns may trigger sustained cytokine release, leading to chronic systemic inflammation, which is hypothesized to underlie the development of chronic fatigue in athletes (50, 51)

These mechanisms still need to be further studied

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