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Because digoxin toxicity can present as nausea and vomiting, symptoms that overlap with GLP-1 RA side effects, maintain a low threshold for checking levels in any patient reporting new or worsening GI symptoms after a GLP-1 RA dose increase

ACSS2 acts as a lactyl-CoA synthetase and couples KAT2A to function as a lactyltransferase for histone lactylation and tumor immune evasion

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Therapeutic approaches targeting glial cells Given the prominent role of glial cells in the onset and progression of ALS, modulating their activity is one of the promising therapeutic strategies in ALS