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Rotating sites may reduce irritation when multiple injections are needed

Do not use in patients with known hypersensitivity to Hydroxocobalamin or cobalt

How much do vitamin B12 injections cost compared to pills

As such, it is difficult to work out if a B12 deficiency and joint pain are because of correlation or causation

While this effect appears to be related to the magnitude and rapidity of glucose lowering rather than a direct effect of the medication itself, patients with a history of diabetic retinopathy should undergo careful ophthalmologic evaluation before and during treatment, and the potential risks should be weighed against the expected benefits of improved glycemic control