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7 GLN causes cellular ferroptosis in an indirect way In clinical settings, radiotherapy remains the mainstay treatment for leukemia, although GLN-targeting agents (e.g., CB-839) have been developed to indirectly induce ROS production [8]

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However, a significant increase in cell viability was observed for -EC (100 M)- and GSH (100 M)-pretreated cells after a 4 h incubation period, suggesting the protective effect of the compounds

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