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These agents always have variations in the aspect of target specificity and pharmacokinetic properties in preclinical studies and clinical settings

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Pham-Short A, Donaghue KC, Ambler G, Phelan H, Twigg S, Craig ME

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The review confirmed GLP-1 receptors are located in reward related areas, and GLP-1, its agonists, and DPP-IV inhibitors are effective in decreasing palatable food intake, along with reducing cocaine, amphetamine, alcohol and nicotine use in animals