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Options include medication to reduce thyroid hormone production, radioactive iodine therapy, or in some cases, surgery

Although CMS has tried to mitigate this issue by making additional clarifications to the Integrated Denial Notice, this has not completely resolved the problem, and CMS has asked for public comment on the form and its instructions (CMS, 2016c)

Improving the efficiency of carnitine absorption and utilization is also possible by improving the mechanism of carnitine transport, such as increasing the expression or activity of carnitine transporters [199, 200]

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