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Its importance cannot be overstated, as a deficiency can lead to serious health issues

Glutathione helps fight infections from bacteria, viruses by priming the white cells that fight infection such as natural killer cells and T-cell lymphocytes (white blood cells)

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This process can consume enormous quantities of NAD+ during periods of high DNA damage burden a situation observed in aged cells where accumulated oxidative and replicative DNA damage drives chronic PARP hyperactivation and consequent NAD+ depletion