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A meta-analysis highlighted some impressive outcomes: an average reduction in waist circumference by 5.16 cm, a BMI drop of 2.42 points, and significant decreases in serum triglyceride levels when compared to placebo treatments

The ASX-treated group showed a significant improvement in ART-related outcomes compared to the placebo group, suggesting that a less inflamed and oxidized environment favors higher fertilization rates, embryo quality, and pregnancy rates

10.1016/S0149-2918(00)88479-9

At the time this article was written, semaglutide was not on the WADA Prohibited List

Sirtuins, particularly SIRT1 and SIRT3, protect cells from oxidative stress by increasing the activity of antioxidant enzymes, including superoxide dismutase 2 (SOD2) and CAT (127, 131, 132)