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ER stress and Ferroptosis JEV and HSV infections trigger rapid aggregation of viral proteins in the ER lumen and stimulate massive ER membrane rearrangements, leading to ER stress and activation of the unfolded protein response (UPR)

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Furthermore, the ratio of H2AX + cells was elevated by pefloxacin, which was reversed by co-treatment with dexamethasone (Figures 6E, F), consistent with the in vivo data (Figures 4F, G)

(PubMed) Rinella ME, Lazarus JV, Ratziu V, et al

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