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Glucagon-like peptide-1 receptor agonists might be disease-modifying in patients with knee osteoarthritis and type 2 diabetes if treatment is sustained for a sufficient period, according to data

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doi: 10.1016/j.neuroscience.2015.03.017 30

AOD-9604 is a modified fragment of growth hormones C-terminal region, which mediates its fat burning effects

Among the numerous beneficial effects mediated by GLP-1R agonists are regulation of blood glucose, lowering of body weight via inhibition of food intake and the decrement of gastric motility, stimulation of cell proliferation, reduction of inflammation and apoptosis, improvement of cardiovascular function, and neuroprotection