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If your pharmacy includes B12 at a lower concentration, you may want to supplement with additional oral or sublingual B12 between injections, especially at lower semaglutide doses where injection volume (and therefore B12 delivery) is minimal

Hawrelak, J.A

Importantly, direct activation of GLP-1Rs within the NTS also suppresses food reward behaviour, reduces operant responding for sucrose, abolishes conditioned place preference for palatable food, and preferentially decreases palatable food intake when animals are given a choice between palatable food and standard chow (53)