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Topical NSAIDs such as diclofenac 1% gel (Voltaren, available over-the-counter in the US) can provide localized pain relief for musculoskeletal conditions with minimal systemic absorption and reduced gastrointestinal risk

Disclosures Disclosure forms, as provided by each author, are available with the online version of the article at Author Contributions Conceptualization: Yuki Sugiura, Motoko Yanagita

Both studies also reported relative safety and no side effects that may otherwise occur with exogenous hGH use [2]: No statistically significant differences in IGF-1 levels were observed among the treatment and placebo groups throughout the study

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