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A buffer consisting of 20 mM HEPES, 100 mM NaCl, pH 7.4, 10 mM MgCl 2 , 1 mM MnCl 2 and 10% glycerol was used to re-suspend the collected membranes

This treatment resulted in a significant reduction in mean PASI and DLQI scores, improved skin lesions, and reduced levels of interleukin (IL)17, IL-23, and tumor necrosis factor alpha (TNF)