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J Pharmacol Exp Ther (2000) 294:6172

Annals of pediatric endocrinology & metabolism, 30(4), 165174

Total weight loss of 8-15 pounds

Phase 3 trials are currently underway, with FDA approval projected between late 2026 and early 2027

Funding This work was supported by grants from The Guangdong Basic and Applied Basic Research Foundation (grant numbers: 2022A1515220187 and 2019A1515111018), National Natural Science Foundation of China (grant number: 82102689), the Excellent Young Researchers Program of the Fifth Affiliated Hospital of Sun Yat-sen University (2023080017 and WYYXQN-2021016), Fundamental Research Funds for the Central Universities of Sun Yat-sen University (grant number: 22qntd3502), the Project of Guiyang Health and Family Planning Commission (grant number: 2018-016), and Yunnan Province Applied Basic Research Program Kunming Medical University Joint Project (202401AY070001-120)