Thyrocytes and thyroid fibroblasts pre-incubated with selenocompounds (selenomethionine and selenite) showed a dose-dependent increase in viability and a decrease in apoptosis indicators (caspase-3 activity, BAX mRNA levels) and an increase in the level of the inhibitor of apoptosis (BCL-2 mRNA) after incubation with H 2 O 2 , and also caused an increase in GPx activity (66)
Its deficiency, although rare, may present with dermatitis, brittle nails, and hair loss (248)
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However, its clinical application is hindered by bioavailability and stability challenges, which are being addressed through innovative formulations and emerging technologies
albicans systemic infections by enabling the hyphae to penetrate endothelial tissue and subsequently seed the bloodstream with yeast cells 1,2,3
