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Findings vary depending on study design, model type, and experimental parameters

There is also no data available on what happens with long-term use of MOTS-c

Metaflammation (inflammation of metabolism) Inflammation linked to insulin resistance, obesity, or chronic stress

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Also, we should acknowledge that animal models although quite different (Schachtrupp et al., 2007) (here, 25, 30, 40, and 50 mm Hg by intraperitoneal insufflation of ordinary air controlled and maintained by a manual manometer leads to invariable abdominal compartment syndrome), correlate fairly well with the circumstances in humans