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5.2 Regulation of T cell subtypes CD4/CD8 and Treg cells by GLP-1RA GLP-1R is expressed in various immune cell populations of NOD mice, with a higher proportion of mature CD4 + and CD8 + T cells (approximately 5%-6%)

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Poorly controlled diabetes increases the fetal risk for major birth defects, still birth, and macrosomia related morbidity

This article examines the relationship between GLP-1 therapy and heart rate, explores the underlying mechanisms, reviews cardiovascular safety data, and provides guidance on when to seek medical advice